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Phase 2 study. ALG 1007, a peptide integrin inhibitor is being developed by Allegro Ophthalmics for the treatment of dry eye disease (DED). ALG 1007 inhibits the leucocyte ALG 1007 - AdisInsight ALG-1007 is a topical treatment in development for potential use in patients with dry eye disease (DED), a condition affecting millions of people in the United States. ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate ® ), currently being developed for diabetic macular edema (DME) and intermediate ALG-1007 is a topical treatment in development for potential use in patients with dry eye disease (DED), a condition affecting millions of people in the United States. ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate),currently being developed for diabetic macular edema (DME) and intermediate dry age-related macular degeneration (intermediate 2020-09-21 Allegro has a clear path forward and is gearing up for a larger US Phase 2b/3 trial in dry AMD in 1H 2020 ALG-1007 for topical use in dry eye disease demonstrated an improvement in both signs and symptoms of DED Allegro has initiated a second larger exploratory ex-US DED study looking at higher doses in a vehicle-controlled study “ALG-1007 represents Allegro’s first exploratory drug beyond the retina. We recognize the need to bring in independent external expertise that complements our company’s strengths and are thrilled to have such an outstanding group of advisors as Drs. Lindstrom, Holland and Donnenfeld help shape and accelerate our clinical program for dry eye disease.” 2020-09-21 Allegro Ophthalmics announced positive results of an ex-US proof-of-concept clinical trial of the new investigational ALG-1007 topical drop drug candidate in patients with dry eye disease (DED). The results were presented by Eric D. Donnenfeld, MD, last week at the 2019 American Society of Cataract and Refractive Surgery and American Society of Ophthalmic Administrators (ASCRS•ASOA) Annual … ALG-1007 has successfully completed an ex-U.S.

This website contains many kinds of images but only a few are being shown on the homepage or in search results. In addition to these picture-only galleries, you ALG-1007 is a topical integrin regulator in development for potential use in patients with dry eye disease. ALG-1007 demonstrated a strong signal in an ex-U.S. proof-of-concept clinical trial in which it showed a dose response curve and that it was generally well-tolerated. Expanding its anti-integrin portfolio, Allegro has developed ALG-1007, an anti-integrin drug candidate for topical use in DED. ALG-1007 has successfully completed an ex-U.S. proof-of-concept study in humans, and is currently being evaluated in a larger ex-U.S. Phase 2 study.

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“These early results suggest that ALG-1007 improves the signs and symptoms of dry eye, a disease that affects millions of people globally, with symptoms that include scratchy, stinging or burning sensations, and pain or 2019-05-17 · Results announced from ex-U.S. proof-of-concept trial with ALG-1007 for dry eye At its highest dose concentration (0.6%), the new investigational topical drug ALG-1007 (Allegro Ophthalmics) had statistically significant efficacy in nearly all assessments for dry eye and a more rapid onset of action compared to the lowest dose (0.125%), according to a company press release.

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For more information, visit www.allegroeye.com . ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate ® ), currently being developed for diabetic macular edema (DME) and intermediate dry age “Allegro is continuously exploring new ways to apply our anti-integrin portfolio to help improve patients’ vision, and ALG-1007 represents our first exploratory drug for the potential treatment of dry eye, a disease that adversely affects millions of Americans.” The corporate … “Allegro is excited to share our ex-U.S. proof-of-concept data of ALG-1007 for dry eye disease,” said Vicken Karageozian, M.D., President and CEO of Allegro Ophthalmics.

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ALG-1007 is a topical integrin regulator in development for potential use in patients with dry eye disease. ALG-1007 demonstrated a strong signal in an ex-U.S. proof-of-concept clinical trial in which it showed a dose response curve and that it was generally well-tolerated. A second and larger ex-U.S.

proof-of-concept clinical trial of the new investigational ALG-1007 topical drop drug candidate in patients with dry eye disease (DED).
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Allegro Ophthalmics announced the expansion of the company’s anti-integrin portfolio with the new topical dry eye disease drug candidate ALG-1007. ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate), currently being developed for diabetic macular edema (DME) and intermediate dry age-related “ALG-1007 represents Allegro’s first exploratory drug beyond the retina. We recognize the need to bring in independent external expertise that complements our company’s strengths and are ALG-1007 is a topical treatment in development for potential use in patients with dry eye disease (DED), a condition affecting millions of people in the United States. ALG-1007 bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate),currently being developed for diabetic macular edema (DME) and intermediate Allegro Ophthalmics, LLC has announced earlier this week the company’s expansion of its anti-integrin portfolio with the new front-of-the-eye-drug candidate ALG-1007. ALG-1007 is a topical treatment in development for potential use in patients with dry eye disease (DED), a condition affecting millions of people in the United States.

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