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Mutations in this gene can cause immunodeficiency . STAT1 phosphorylation, dimerization, and translocation to the nucleus will induce target gene transcription and expression. Following gene activation, STAT1 dimers dephosporylate, detach from the nucleus, and are translocated back to the cytoplasm.152–154 STAT1 mutations had been known to underlie mycobacterial and viral diseases. Signal transducer and activator of transcription 3 (STAT3) is a transcription factor which in humans is encoded by the STAT3 gene. It is a member of the STAT protein family.

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Stat gene

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Stat gene

Cytoplasmic and nuclear expression in selected tissues, most abundant in lymphoid tissues. More details on the stat module can be found in the qbase+ manual. More than 15 years of research experience and interaction with course participants indicates that the majority of gene expression questions can be addressed by the tests built into qbase+.

Stat gene

Summary. The protein encoded by this gene is a member of the STAT family of transcription factors.
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This is why StrateGene® presents your genetic findings in Pathways, which are visual interpretations  STAT, Boston, Massachusetts. 294087 likes · 5097 talking about this · 32 were here.
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Thus for a given STAT-regulated cellular process, it should in principle be possible to identify the gene or genes that STATs activate (or repress) to carry out that process. Indeed, many target genes of STATs have been identified and, based upon their Balanced Stat Gen Download Now When working on large scale games with lots of characters/enemies it can be hard to keep things balanced when coming up with their stats, that's why I decided to create this tool.

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The STAT3 gene is part of a family known as the STAT genes. These genes provide instructions for making proteins that are part of essential chemical signaling pathways within cells. When STAT proteins are activated by certain chemical signals, they move into the nucleus and attach (bind) to specific areas of DNA. Gene ID: 6774, updated on 9-Apr-2021. Summary. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.

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-------Identification and cloning of STAT phosphatase, STAT kinase, and STAT co- activator. Methods: yeast two hybrid system, gene transfer, expression cloning,  It is used for the quantitative determination of B-Hydroxybutyrate in serum or plasma, aiding in the diagnosis and monitoring of ketoacidosis. Genes don't work in isolation, they work together as a team.

The gene view histogram is a graphical view of mutations across STAT6. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. In addition, during ATRA-induced myeloid differentiation, gene expression of STAT1, STAT2, and p48 was upregulated. These proteins are involved in IFN-alpha specific signaling. ATRA-induced expression of IRF and/or STAT transcription factors may be one of the molecular mechanisms mediating growth inhibition by ATRA.